Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 10/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458381 | 0.88 | NAMPT (0.48) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5461007 | 0.87 | RAB9A (0.51) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5469430 | 0.83 | NAMPT (0.47) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5454328 | 0.83 | IDO1 (0.46) | ALDH1A1SMN1; SMN2MAPTRAB9ACASP3 | |
| SCHEMBL5465544 | 0.82 | NPC1 (0.55) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5460036 | 0.81 | PANK3 (0.41) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL5463378 | 0.78 | NPC1 (0.58) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5460127 | 0.76 | MAPT (0.47) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5473690 | 0.76 | GFER (0.60) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL5460590 | 0.73 | MAPT (0.52) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | ALDH1A1 731/4885SMN1; SMN2 4424/4885MAPT 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.