Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | MDM2 | Q00987 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.98 |
| ▸ | MAPT | P10636 | 5/20 | 0.98 |
| ▸ | RAB9A | P51151 | 2/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.98 |
| ▸ | TSHR | P16473 | 3/20 | 0.95 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.95 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.95 |
| ▸ | FLT3 | P36888 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177320 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL5448366 | 0.85 | ALDH1A1 (0.76) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL3922474 | 0.83 | FLT3 (1.00) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL8288845 | 0.82 | FLT3 (0.97) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL3128067 | 0.82 | FLT3 (0.92) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL5455726 | 0.82 | FLT3 (0.97) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL3914689 | 0.82 | FLT3 (0.92) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL3126680 | 0.81 | FLT3 (0.90) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL8288684 | 0.81 | FLT3 (0.90) | ALDH1A1HPGDMDM2KDM4EMAPT | |
| SCHEMBL8290415 | 0.81 | FLT3 (0.90) | ALDH1A1HPGDMDM2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | ALDH1A1 1153/4885HPGD 2361/4885MDM2 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.