Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.73 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.65 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.65 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457507 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HTTNPSR1HPGDHSD17B10 | |
| SCHEMBL18177320 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HTTNPSR1HPGDHSD17B10 | |
| SCHEMBL5453301 | 0.84 | REV1 (0.76) | ALDH1A1HTTNPSR1HPGDHSD17B10 | |
| SCHEMBL5453347 | 0.84 | REV1 (0.76) | ALDH1A1HTTNPSR1HPGDHSD17B10 | |
| SCHEMBL3916303 | 0.83 | REV1 (0.79) | ALDH1A1HPGDHSD17B10MAPTRAB9A | |
| SCHEMBL5451305 | 0.81 | MAPT (0.70) | ALDH1A1HTTNPSR1HPGDHSD17B10 | |
| SCHEMBL3916246 | 0.81 | MAPT (0.78) | ALDH1A1HPGDHSD17B10MAPTRAB9A | |
| SCHEMBL5456030 | 0.79 | MAPT (0.70) | ALDH1A1HPGDHSD17B10MAPTRAB9A | |
| SCHEMBL10143922 | 0.79 | MAPT (1.00) | ALDH1A1HPGDHSD17B10TSHRMAPT | |
| SCHEMBL5462746 | 0.78 | MAPT (0.69) | ALDH1A1HPGDHSD17B10MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | ALDH1A1 1153/4885HTT 44/4885NPSR1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.