SCHEMBL5457508

SCHEMBL5457508

COc1ccc(CNc2ccc([N+](=O)[O-])c3nnoc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.50
KMT2A Q03164 4/20 0.48
MAPT P10636 4/20 0.48
MEN1 O00255 3/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
IDO1 P14902 2/20 0.47
USP2 O75604 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
EGFR P00533 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
IGF1R P08069 1/20 0.45
PRKCQ Q04759 1/20 0.44
HPGD P15428 1/20 0.42
POLB P06746 2/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654531 0.85 MEN1 (0.64) KMT2AMAPTMEN1CRHBPCRHR2
SCHEMBL611015 0.81 KMT2A (0.72) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL4309629 0.76 MAPT (0.62) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL7318993 0.73 MAPT (0.68) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL7066582 0.73 LMNA (0.49) NPC1KMT2AMAPTMEN1IDO1
SCHEMBL14407558 0.72 MAPT (0.58) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL10358222 0.72 MAPT (0.77) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL9683146 0.72 MAPT (0.57) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL28808881 0.72 MAPT (0.57) NPC1KMT2AMAPTMEN1CRHBP
SCHEMBL9681394 0.72 MAPT (0.74) NPC1KMT2AMAPTMEN1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070026130-A1 Method of developing latent fingerprints ARMOR HOLDINGS FORENSICS, INC. 2007-02-01 US claimed
US-20070026130-A1 Method of developing latent fingerprints ARMOR HOLDINGS FORENSICS, INC. 2007-02-01 US disclosed
US-20040077017-A1 Detection methods which rely on association between the target molecule and a binding partner AFFIBODY AB (SE) 2004-04-22 US disclosed
EP-1352242-A2 DETECTION METHODS Affibody AB (SE) 2003-10-15 EP disclosed
WO-2002056024-A2 DETECTION METHODS AFFIBODY AB (SE) 2002-07-18 WO disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
EP-0532798-B1 An electroluminescent element ASAHI CHEMICAL IND (JP) 1995-12-06 EP disclosed
US-5281489-A Anode, cathode, organic luminescent layer disposed between, the luminescent layer comprising a fluorescent luminescent agent, a hole moving and donating agent, an electron moving and donating agent ASASHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-25 US disclosed
EP-0532798-A1 An electroluminescent element ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-03-24 EP disclosed
WO-1991005605-A1 CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-05-02 WO disclosed