Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164868 | 0.88 | MAPT (0.84) | MAPTL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL31382898 | 0.87 | NPC1 (0.59) | MAPTL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL3400808 | 0.86 | SMN1; SMN2 (0.70) | MAPTL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL4309629 | 0.86 | MAPT (0.62) | MAPTL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL10360050 | 0.84 | MAPT (0.73) | MAPTL3MBTL1RAB9AKMT2ALMNA | |
| SCHEMBL21608415 | 0.83 | NPC1 (0.56) | MAPTL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL6474847 | 0.83 | HTR6 (0.58) | MAPTL3MBTL1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL2130528 | 0.83 | MAPT (0.60) | MAPTL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL102602 | 0.83 | MAPT (0.77) | MAPTL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL14407558 | 0.82 | MAPT (0.58) | MAPTL3MBTL1NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024056019-A1 | BICYCLIC COMPOUNDS AS CDK INHIBITORS | BEIGENE, LTD. (KY) | 2024-03-21 | — | — | WO | disclosed |
| CN-106986861-A | Antiviral compound | 艾伯维巴哈马有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-103819459-B | Anti-Viral Compounds | 艾伯维巴哈马有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-102333772-A | Antiviral compounds | ABBOTT LAB | 2012-01-25 | — | — | CN | disclosed |
| US-20070212267-A1 | Method and apparatus for performing micro-scale chemical reactions | TOTAL SYNTHESIS LTD. (CA) | 2007-09-13 | — | — | US | disclosed |
| US-20070212267-A1 | Method and apparatus for performing micro-scale chemical reactions | TOTAL SYNTHESIS LTD. (CA) | 2007-09-13 | — | — | US | disclosed |
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | disclosed |
| CN-1176646-A | CCK or gastrin modulating 5 -heterocyclic-1, 5-benzodiazepines | GLAXO WELLCOME INC (US) | 1998-03-18 | — | — | CN | disclosed |
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0190817-B1 | DOPAMINE-BETA-HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |
| US-4857540-A | 1-SUBSTITUTED-2-MERCAPTO-(OR AMINOMETHYL-)BENZAMIDAZOLE COMPOUNDS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4728741-A | DOPAMINE BETA-HYDROXYLASE INHIBITOR | SMITHKLINE BECKMAN CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0190817-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1986-08-13 | — | — | EP | disclosed |