SCHEMBL545752

SCHEMBL545752

CCCCCCCCCCCC[N+](C)(C)CCCOS(=O)(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 7/20 0.55
HTT P42858 2/20 0.54
KMT2A Q03164 1/20 0.45
CA1 P00915 8/20 0.44
CA2 P00918 8/20 0.44
CA9 Q16790 7/20 0.44
CA12 O43570 3/20 0.44
CA7 P43166 3/20 0.44
CA14 Q9ULX7 3/20 0.44
CA3 P07451 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CA5B Q9Y2D0 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1572937 1.00 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
SCHEMBL6858953 1.00 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
SCHEMBL8885118 1.00 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
Hydrochloric Acid SCHEMBL8961957 0.98 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
Water SCHEMBL2687246 0.98 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
Hydrochloric Acid SCHEMBL8962131 0.98 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
Water SCHEMBL2025641 0.98 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
Bromide SCHEMBL10492709 0.98 DNM1 (0.57) DNM1HTTKMT2ACA1CA2
SCHEMBL8436911 0.96 DNM1 (0.55) DNM1HTTCA1CA2CA9
SCHEMBL8884394 0.96 DNM1 (0.55) DNM1HTTCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6989195-B2 Coated particles, methods of making and using LYOTROPIC THERAPEUTICS, INC. (US) 2006-01-24 US claimed
US-20040201117-A1 COATED PARTICLES, METHODS OF MAKING AND USING ANDERSON DAVID (US) 2004-10-14 US claimed
US-20210015796-A1 TREATMENT USING DANTROLENE LYOTROPIC THERAPEUTICS INC (US) 2021-01-21 US disclosed
EP-1603513-B1 DANTROLENE COMPOSITIONS LYOTROPIC THERAPEUTICS INC (US) 2020-12-30 EP disclosed
US-10821098-B2 Treatment using dantrolene LYOTROPIC THERAPEUTICS, INC. (US) 2020-11-03 US disclosed
US-10597298-B2 Ceramic encapsulation by use of one or more specialized silanes to template oil in an oil in water emulsion CoLabs International Corporation (US) 2020-03-24 US disclosed
US-20190255021-A1 TREATMENT USING DANTROLENE LYOTROPIC THERAPEUTICS INC (US) 2019-08-22 US disclosed
US-10314822-B2 Treatment using dantrolene LYOTROPIC THERAPEUTICS, INC. (US) 2019-06-11 US disclosed
US-20180125822-A1 TREATMENT USING DANTROLENE LYOTROPIC THERAPEUTICS INC (US) 2018-05-10 US disclosed
US-20180037464-A1 Ceramic Encapsulation by Use of One or More Specialized Silanes to Template Oil in an Oil in Water Emulsion CoLabs International Corporation (US) 2018-02-08 US disclosed
US-9884044-B2 Treatment using dantrolene LYOTROPIC THERAPEUTICS, INC. (US) 2018-02-06 US disclosed
EP-0942780-A4 COATED PARTICLES, METHODS OF MAKING AND USING SELECT RELEASE L C (US) 2001-01-10 EP disclosed
US-6004771-A EXTRACTED MYCOBACTERIAL SAMPLE IS SUITABLE FOR DETECTION BY CULTURE AND AMPLIFICATION INTEGRATED RESEARCH TECHNOLOGY, LLC (US) 1999-12-21 US disclosed
EP-0942780-A1 COATED PARTICLES, METHODS OF MAKING AND USING Select Release, L.C. (US) 1999-09-22 EP disclosed
WO-1999012640-A1 COATED PARTICLES, METHODS OF MAKING AND USING SELECT RELEASE, L.C. (US) 1999-03-18 WO disclosed
US-5880076-A PERSONAL PRODUCT OR DETERGENT COMPOSITION COMPRISING CYCLIC GLYCACARBAMATE AND/OR GLYCAUREA, SURFACTANT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1999-03-09 US disclosed
US-5658749-A DECREASING THE BUOYANCY OF MICROORGANISMS CONTAINING MYCOLIC ACID-LIKE STRUCTURES IN THE OUTER MEMBRANE USING A SOLUTION OF AN SB-18-LIKE OR ROD-LIKE DETERGENT; AMPHOTERIC SURFACTANTS; MEDICAL DIAGNOSIS; CULTURES; AMPLIFICATION CORNING CLINICAL LABORATORIES, INC. (US) 1997-08-19 US disclosed
US-5653970-A CLEANING COMPOUNDS; COSMETICS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-08-05 US disclosed
US-5641480-A ENHANCED STABILITY AND/OR VISCOSITY, CLARITY LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-06-24 US disclosed
US-5624906-A Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-04-29 US disclosed