Water

Water

SCHEMBL2025641

CCCCCCCCC[N+](C)(C)CCCOS(=O)(=O)O.[OH-]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 7/20 0.53
HTT P42858 2/20 0.52
KMT2A Q03164 1/20 0.44
CA1 P00915 8/20 0.43
CA2 P00918 8/20 0.43
CA9 Q16790 7/20 0.43
CA12 O43570 3/20 0.43
CA7 P43166 3/20 0.43
CA14 Q9ULX7 3/20 0.43
CA3 P07451 2/20 0.43
CA4 P22748 2/20 0.43
CA6 P23280 2/20 0.43
CA5A P35218 2/20 0.43
CA5B Q9Y2D0 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2687246 1.00 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
SCHEMBL8885118 0.98 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
SCHEMBL1572937 0.98 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
SCHEMBL545752 0.98 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
SCHEMBL6858953 0.98 DNM1 (0.55) DNM1HTTKMT2ACA1CA2
Hydrochloric Acid SCHEMBL8962131 0.97 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
Hydrochloric Acid SCHEMBL8961957 0.97 DNM1 (0.53) DNM1HTTKMT2ACA1CA2
Bromide SCHEMBL10492709 0.97 DNM1 (0.57) DNM1HTTKMT2ACA1CA2
SCHEMBL8436911 0.95 DNM1 (0.55) DNM1HTTCA1CA2CA9
SCHEMBL8884394 0.95 DNM1 (0.55) DNM1HTTCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824915-B Preparation method of high-performance conductive polymer hydrogel 江西科技师范大学 2021-09-14 CN claimed
US-20120114718-A1 SOLID-STATE METHOD FOR PRODUCING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID ORGANIC/INORGANIC CHEMICAL SYSTEMS FOR DENTAL REMINERALIZATION APPLICATIONS KARLINSEY ROBERT L (US) 2012-05-10 US claimed
EP-2120842-A2 HYBRID ORGANIC/INORGANIC CHEMICAL HYBRID SYSTEMS, INCLUDING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS, AND A SOLID-STATE METHOD OF PRODUCING THE SAME Indiana Nanotech Division of Therametric Technologies, INC. (US) 2009-11-25 EP claimed
WO-2008137190-A2 HYBRID ORGANIC/INORGANIC CHEMICAL HYBRID SYSTEMS, INCLUDING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS, AND A SOLID-STATE METHOD OF PRODUCING THE SAME INDIANA NANOTECH DIVISION OF THERAMETRIC TECHNOLOGIES, INC. (US) 2008-11-13 WO claimed
US-20080187500-A1 HYBRID ORGANIC/INORGANIC CHEMICAL HYBRID SYSTEMS, INCLUDING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS, AND A SOLID-STATE METHOD FOR PRODUCING THE SAME INDIANA NANOTECH 2008-08-07 US claimed
CN-109824915-B Preparation method of high-performance conductive polymer hydrogel 江西科技师范大学 2021-09-14 CN disclosed
EP-2120842-B1 HYBRID ORGANIC/INORGANIC CHEMICAL HYBRID SYSTEMS, INCLUDING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS, AND A SOLID-STATE METHOD OF PRODUCING THE SAME INDIANA NANOTECH DIVISION OF THERAMETRIC TECH INC (US) 2019-08-21 EP disclosed
US-9023373-B2 Functionalized calcium phosphate hybrid systems for the remineralization of teeth and a method for producing the same INDIANA NANOTECH (US) 2015-05-05 US disclosed
US-20150038362-A1 High-Throughput Method For Sialic Acid Quantitation BIOGEN MA INC. 2015-02-05 US disclosed
EP-2820149-A1 HIGH-THROUGHPUT METHOD FOR SIALIC ACID QUANTITATION Biogen Idec MA Inc. (US) 2015-01-07 EP disclosed
US-8911562-B2 Cleaning compositions for removing organic deposits on surfaces and method of use GONZALEZ MARCO T (US) 2014-12-16 US disclosed
US-20140161797-A1 Injectable Non-Aqueous Suspension DURECT CORPORATION (US) 2014-06-12 US disclosed
EP-1827376-A1 VISCO-SUPPLEMENT COMPOSITION AND METHODS Alza Corporation (US) 2007-09-05 EP disclosed
US-20070037942-A1 Preparation of reactive polymeric nanoparticles BORBELY JANOS 2007-02-15 US disclosed
WO-2006071613-A2 INJECTABLE NON-AQUEOUS SUSPENSION ALZA CORPORATION (US) 2006-07-06 WO disclosed
WO-2006071694-A1 VISCO-SUPPLEMENT COMPOSITION AND METHODS ALZA CORPORATION (US) 2006-07-06 WO disclosed
WO-2006071693-A2 INJECTABLE NON-AQUEOUS SUSPENSION ALZA CORPORATION (US) 2006-07-06 WO disclosed
US-20060141040-A1 Injectable non-aqueous suspension DURECT CORPORATION 2006-06-29 US disclosed
US-20060142234-A1 Injectable non-aqueous suspension DURECT CORPORATION 2006-06-29 US disclosed
US-20060140988-A1 Visco-supplement composition and methods DURECT CORPORATION 2006-06-29 US disclosed