Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8962131 | 1.00 | DNM1 (0.53) | DNM1HTTPLA2G1BHSP90AA1RAD52 | |
| SCHEMBL8885118 | 0.98 | DNM1 (0.55) | DNM1HTTKMT2ACA1CA2 | |
| SCHEMBL545752 | 0.98 | DNM1 (0.55) | DNM1HTTKMT2ACA1CA2 | |
| SCHEMBL1572937 | 0.98 | DNM1 (0.55) | DNM1HTTKMT2ACA1CA2 | |
| SCHEMBL6858953 | 0.98 | DNM1 (0.55) | DNM1HTTKMT2ACA1CA2 | |
| Water SCHEMBL2687246 | 0.97 | DNM1 (0.53) | DNM1HTTKMT2ACA1CA2 | |
| Bromide SCHEMBL10492709 | 0.97 | DNM1 (0.57) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Water SCHEMBL2025641 | 0.97 | DNM1 (0.53) | DNM1HTTKMT2ACA1CA2 | |
| SCHEMBL8436911 | 0.95 | DNM1 (0.55) | DNM1HTTCA1CA2CA9 | |
| SCHEMBL8884394 | 0.95 | DNM1 (0.55) | DNM1HTTCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585472-A | CATALYTIC REACTION OF ALCOHOLS WITH MONOSACCHARIDES USING ACID FORM OF AMPHOTERIC SURFACTANTS AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |