Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.60 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 14/20 | 0.57 |
| ▸ | CNR1 | P21554 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.52 |
| ▸ | PTPRE | P23469 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449174 | 0.91 | CFTR (0.55) | KMT2ANOD1CFTRCNR2CNR1 | |
| SCHEMBL5453343 | 0.86 | CFTR (0.54) | KMT2ANOD1CFTRCNR2CNR1 | |
| SCHEMBL5459324 | 0.85 | CFTR (0.55) | KMT2ANOD1CFTRCNR2CNR1 | |
| SCHEMBL5449075 | 0.83 | CFTR (0.66) | KMT2ACFTRCNR2CNR1ALDH1A1 | |
| SCHEMBL8290653 | 0.81 | CFTR (0.67) | KMT2ACFTRCNR2ALDH1A1HSD17B10 | |
| SCHEMBL5445117 | 0.81 | PTPRC (0.65) | KMT2ACFTRCNR2CNR1ALDH1A1 | |
| SCHEMBL5460329 | 0.80 | CFTR (0.62) | KMT2ACFTRCNR2CNR1ALDH1A1 | |
| SCHEMBL5444948 | 0.79 | FLT3 (0.70) | KMT2ACFTRCNR2ALDH1A1HSD17B10 | |
| SCHEMBL5451324 | 0.78 | CFTR (0.54) | KMT2ACFTRCNR2CNR1ALDH1A1 | |
| SCHEMBL5449732 | 0.78 | ALDH1A1 (0.73) | CFTRCNR2CNR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | KMT2A 4785/4885NOD1 370/4885CFTR 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.