SCHEMBL11686142

SCHEMBL11686142

OCc1cccc(Cc2ccccc2O)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.67
KEAP1 Q14145 1/20 0.48
TSHR P16473 2/20 0.43
CYP2D6 P10635 1/20 0.43
HIF1A Q16665 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
AKR1B1 P15121 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
IDO1 P14902 2/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CYBB P04839 1/20 0.40
CA9 Q16790 1/20 0.39
MPO P05164 1/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874252 0.91 HSPA5 (0.80) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL5852506 0.91 HSPA5 (0.80) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL54577 0.91 HSPA5 (0.80) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL23486766 0.89 GABRA1 (0.50) HSPA5TSHRGABRA1GABRB2CA2
SCHEMBL124524 0.89 GABRA1 (0.50) HSPA5TSHRGABRA1GABRB2CA2
SCHEMBL8583175 0.85 HSPA5 (0.76) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL14595234 0.83 HSPA5 (0.67) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL49745 0.82 HSPA5 (1.00) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL29357407 0.82 HSPA5 (1.00) HSPA5KEAP1TSHRCYP2D6HIF1A
SCHEMBL196227 0.82 GABRA1 (0.57) HSPA5TSHRGABRA1GABRB2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200299195-A1 Salt Inert/Resistant Barrier Compositions and Their Industrial Application WESTMORELAND ADVANCED MAT INC (US) 2020-09-24 US disclosed
US-20150307678-A1 PARTICLE REINFORCED CELLULAR FOAM AND PREPARATION METHOD THEREOF INDUSTRIAL CORPORATION FOUNDATION CHONBUK NATIONAL UNIVERSITY (KR) 2015-10-29 US disclosed
US-20150307678-A1 PARTICLE REINFORCED CELLULAR FOAM AND PREPARATION METHOD THEREOF INDUSTRIAL CORPORATION FOUNDATION CHONBUK NATIONAL UNIVERSITY (KR) 2015-10-29 US disclosed
US-4018847-A EPOXY AND PHENOLIC RESINS THE B. F. GOODRICH COMPANY (US) 1977-04-19 US disclosed