SCHEMBL5458

SCHEMBL5458

COc1cccc(C(=O)O)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
HTT P42858 1/20 0.59
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
KDM4E B2RXH2 6/20 0.57
HPGD P15428 5/20 0.57
HSD17B10 Q99714 5/20 0.57
ALDH1A1 P00352 4/20 0.57
ALOX15 P16050 2/20 0.57
MAPK1 P28482 2/20 0.57
LMNA P02545 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
ALOX12 P18054 1/20 0.57
TLR2 O60603 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360359 1.00 MAPT (0.59) MAPTTDP1HTTCA12CA1
SCHEMBL23277173 0.98 MAPT (0.58) MAPTTDP1HTTCA12CA1
SCHEMBL8649813 0.98 MAPT (0.58) MAPTTDP1HTTCA12CA1
SCHEMBL30463054 0.86 KDM4E (0.59) MAPTHTTCA12CA1CA2
SCHEMBL480276 0.86 KDM4E (0.59) MAPTTDP1HTTCA12CA1
SCHEMBL22588880 0.84 KDM4E (0.57) MAPTTDP1HTTCA12CA1
SCHEMBL29502905 0.84 LMNA (0.57) MAPTHTTCA12CA1CA2
SCHEMBL2066210 0.84 KDM4E (0.57) MAPTTDP1HTTCA12CA1
SCHEMBL312140 0.84 LMNA (0.57) MAPTHTTCA12CA1CA2
SCHEMBL5187364 0.83 ALDH1A1 (0.55) MAPTTDP1HTTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3181 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031336-A Whitening and freckle-removing composition based on multi-channel synergy and application thereof 广州诺彦生物科技有限公司 2026-05-15 CN claimed
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 US claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 EP claimed
US-20250213446-A1 SKIN CARE COMPOSITION PROCTER & GAMBLE (US) 2025-07-03 US claimed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
CN-118880486-B Cool polyester fiber and preparation method thereof 江苏恒科新材料有限公司 2025-06-24 CN claimed
US-12280132-B2 Skin care composition THE PROCTER & GAMBLE COMPANY (US) 2025-04-22 US claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
EP-0225189-A2 Targeted enteral delivery system R.P. SCHERER CORPORATION (US) 1987-06-10 EP claimed
EP-0035770-B1 AN ORALLY ADMINISTERED DRUG FORM COMPRISING A GLYCOSIDIC ANTIBIOTIC AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1986-12-30 EP claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4470980-A Method of increasing oral absorption of β-lactam antibiotics INTERX RESEARCH CORP. (US) 1984-09-11 US claimed
US-4464363-A HYDROXY ARYL- OR HYDROXY ARALKYL ACIDS OR SALTS MERCK & CO., INC. (US) 1984-08-07 US claimed
US-4406896-A ANTIBIOTICS, ACIDS, HYDROXY MERCK & CO., INC. (US) 1983-09-27 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed