Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.56 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502905 | 1.00 | LMNA (0.57) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL480276 | 0.86 | KDM4E (0.59) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL30463054 | 0.86 | KDM4E (0.59) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL5458 | 0.84 | MAPT (0.59) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL22588880 | 0.84 | KDM4E (0.57) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL29360359 | 0.84 | MAPT (0.59) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL2066210 | 0.84 | KDM4E (0.57) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL23277173 | 0.82 | MAPT (0.58) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL1355519 | 0.82 | ALDH1A1 (0.55) | LMNAMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL31346662 | 0.82 | KDM4E (0.56) | LMNAMAPK1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109001342-B | High performance liquid chromatography method for detecting N-2, 3-dimethoxybenzyl piperonylethylamine and salt content thereof | 东北制药集团股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| US-6281320-B1 | POLYOLEFIN CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-08-28 | — | — | US | claimed |
| EP-4626412-A1 | FORMULATION COMPRISING APOCYNIN AND PAEONOL | AKL Research&Development Ltd (GB) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115926-A1 | FORMULATION COMPRISING APOCYNIN AND PAEONOL | AKL RESEARCH & DEVELOPMENT LTD (GB) | 2024-06-06 | — | — | WO | disclosed |
| CN-116999417-A | Liquid preparation containing paeonol and apocynin | AKL研究发展有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-20230330017-A1 | LIQUID FORMULATION COMPRISING PAEONOL AND APOCYNIN | AKL RES & DEVELOPMENT LTD (GB) | 2023-10-19 | — | — | US | disclosed |
| CN-111372572-B | Liquid preparation containing paeonol and apocynin | AKL研究发展有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116514788-A | Chromone mTOR inhibitor, and pharmaceutical composition and application thereof | 贵州医科大学 | 2023-08-01 | — | — | CN | disclosed |
| US-11701325-B2 | Liquid formulation comprising paeonol and apocynin | AKL RESEARCH & DEVELOPMENT LTD (GB) | 2023-07-18 | — | — | US | disclosed |
| US-20220227739-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR | PROTEOSTASIS THERAPEUTICS INC (US) | 2022-07-21 | — | — | US | disclosed |
| EP-4019005-A1 | LIQUID FORMULATION COMPRISING PAEONOL AND APOCYNIN | AKL Research&Development Ltd (GB) | 2022-06-29 | — | — | EP | disclosed |
| US-4639477-A | AZO DYES | CIBA-GEIGY CORPORATION (US) | 1987-01-27 | — | — | US | disclosed |
| EP-0169167-A2 | Process for dyeing high-molecular organic materials, and metal complexes | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| EP-0168343-A2 | Metal complexes, process for their preparation and their use in dyeing high-molecular organic materials | CIBA-GEIGY AG (CH) | 1986-01-15 | — | — | EP | disclosed |
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701325-B2 | Liquid formulation comprising paeonol and apocynin | LPL, PNLIP, LPO | LMNA 312/4885MAPT 1112/4885MAPK1 2242/4885 |
| US-20230330017-A1 | LIQUID FORMULATION COMPRISING PAEONOL AND APOCYNIN | LPL, PNLIP, LPO | LMNA 312/4885MAPT 1112/4885MAPK1 2242/4885 |
| US-20220227739-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR | CFTR, SCNN1B, SCNN1G | LMNA 2133/4885MAPT 4767/4885MAPK1 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.