Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152197 | 0.89 | TP53 (0.65) | TP53ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL14428687 | 0.85 | KMT2A (0.70) | TP53ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL14428692 | 0.84 | ALDH1A1 (0.56) | TP53ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL14440389 | 0.83 | ALDH1A1 (0.57) | TP53ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5175155 | 0.82 | ATM (0.58) | TP53ALDH1A1KDM4ESMN1; SMN2ATM | |
| SCHEMBL5174830 | 0.73 | HTR3A (0.52) | ALDH1A1LMNASMN1; SMN2TSHRRECQL | |
| SCHEMBL5175280 | 0.73 | ALDH1A1 (0.62) | TP53ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5173004 | 0.73 | KMT2A (0.57) | TP53ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL25010275 | 0.69 | NAMPT (0.66) | TSHRKMT2AMEN1 | |
| SCHEMBL2217529 | 0.68 | KMT2A (0.86) | TP53ALDH1A1SMN1; SMN2ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191400-A1 | Pharmaceutical compositions comprising anti-inflammatory quinazolinecarboxamide derivatives | RIMONYX PHARMACEUTICALS LTD. (IL) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191400-A1 | Pharmaceutical compositions comprising anti-inflammatory quinazolinecarboxamide derivatives | HPSE, SSB, HCLS1 | TP53 802/4885ALDH1A1 2758/4885KDM4E 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.