Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclobarbital SCHEMBL157224 | 0.83 | MEN1 (0.44) | MEN1KMT2AMMP2MMP3MMP9 | |
| Cyclobarbital SCHEMBL1256543 | 0.81 | MEN1 (0.43) | MEN1KMT2AMMP2MMP3MMP9 | |
| Heptabarbital SCHEMBL713359 | 0.81 | MEN1 (0.43) | MEN1KMT2AMMP2MMP3MMP9 | |
| Cyclobarbital SCHEMBL7698655 | 0.80 | MEN1 (0.42) | MEN1KMT2AMMP2MMP3MMP9 | |
| Phenobarbital SCHEMBL7775273 | 0.76 | MMP9 (0.53) | MEN1KMT2AMMP2MMP3MMP9 | |
| Cyclobarbital SCHEMBL22231503 | 0.75 | AKR1B1 (0.39) | MEN1KMT2AMMP2MMP3MMP9 | |
| Cyclobarbital SCHEMBL5458050 | 0.75 | HCAR2 (0.40) | MEN1KMT2AMMP2MMP3MMP9 | |
| Cyclobarbital SCHEMBL23533905 | 0.71 | HCAR2 (0.36) | MEN1KMT2A | |
| Barbituric Acid SCHEMBL691401 | 0.69 | SRC (0.33) | — | |
| Barbituric Acid SCHEMBL45717 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139204-A2 | FUNCTIONAL GROUP IMPRINTED POLYMERS | IMPERIAL INNOVATIONS LTD (GB) | 2008-11-20 | — | — | WO | disclosed |