Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767872 | 0.86 | KMT2A (0.72) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14096532 | 0.86 | KMT2A (0.72) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28330757 | 0.85 | SIRT1 (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL16358841 | 0.85 | KMT2A (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14127097 | 0.84 | EPHX1 (0.78) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14860311 | 0.84 | EPHX1 (0.78) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5457898 | 0.84 | ALDH1A1 (0.81) | KMT2AMEN1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10192214 | 0.84 | RAB9A (0.81) | KMT2AMEN1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL3223877 | 0.84 | RAB9A (0.81) | KMT2AMEN1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL14096413 | 0.84 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |