Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904409 | 0.75 | ALDH1A1 (0.46) | RAB9ALMNAHTTSMN1; SMN2TAAR1 | |
| SCHEMBL6357879 | 0.71 | ALDH1A1 (0.46) | NPC1RAB9ALMNANPSR1HTT | |
| SCHEMBL11452419 | 0.71 | NOS1 (1.00) | NOS1CYP2D6NOS3NOS2CYP3A4 | |
| SCHEMBL14732897 | 0.70 | ALDH1A1 (0.48) | NPC1RAB9ALMNAHTTSMN1; SMN2 | |
| SCHEMBL9191031 | 0.68 | IDO1 (0.69) | NOS1CYP2D6NOS3NOS2CYP3A4 | |
| SCHEMBL2552339 | 0.67 | ALDH1A1 (0.46) | NPC1RAB9ALMNAHTTALDH1A1 | |
| SCHEMBL5322137 | 0.67 | ALDH1A1 (0.46) | NPC1RAB9ALMNANPSR1HTT | |
| SCHEMBL31703749 | 0.67 | — | — | |
| SCHEMBL4316762 | 0.67 | NOS1 (1.00) | NOS1CYP2D6NOS3NOS2CYP3A4 | |
| SCHEMBL30473425 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |