Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596668 | 0.83 | MAPT (0.55) | LMNAGAACYP1A2ALDH1A1TAS2R38 | |
| SCHEMBL5464300 | 0.82 | ALDH1A1 (0.66) | LMNACYP1A2ALDH1A1MAPK1EGFR | |
| SCHEMBL5444750 | 0.80 | MAPK1 (0.67) | LMNACYP1A2ALDH1A1TAS2R38MAPK1 | |
| SCHEMBL5449574 | 0.79 | EGFR (0.68) | LMNACYP1A2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL6294952 | 0.78 | NPSR1 (0.62) | CYP1A2ALDH1A1HSD17B10MEN1NPC1 | |
| SCHEMBL5463525 | 0.78 | LMNA (0.81) | LMNAGAACYP1A2ALDH1A1MAPK1 | |
| SCHEMBL17956765 | 0.77 | EGFR (0.61) | LMNACYP1A2ALDH1A1MAPK1EGFR | |
| SCHEMBL5457374 | 0.76 | CYP1A2 (1.00) | LMNAGAACYP1A2ALDH1A1TAS2R38 | |
| SCHEMBL5455171 | 0.76 | MEN1 (0.71) | LMNACYP1A2ALDH1A1TAS2R38HSD17B10 | |
| SCHEMBL1276484 | 0.73 | ALDH1A1 (0.64) | LMNAGAACYP1A2ALDH1A1TAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |