Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17956765 | 0.93 | EGFR (0.61) | EGFRERBB2MAPTHTTCYP1A2 | |
| SCHEMBL5455537 | 0.91 | ALDH1A1 (0.69) | EGFRERBB2MAPTHTTALDH1A1 | |
| SCHEMBL5464300 | 0.89 | ALDH1A1 (0.66) | EGFRERBB2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL8829693 | 0.87 | EGFR (0.58) | EGFRERBB2MAPTHTTCYP1A2 | |
| SCHEMBL5444750 | 0.83 | MAPK1 (0.67) | MAPTCYP1A2ALDH1A1MAPK1LMNA | |
| SCHEMBL2448810 | 0.81 | HDAC6 (0.65) | EGFRHTTALDH1A1KMT2A | |
| SCHEMBL5458207 | 0.79 | LMNA (0.65) | EGFRERBB2CYP1A2ALDH1A1MAPK1 | |
| SCHEMBL11865208 | 0.79 | CYP1A2 (0.64) | EGFRERBB2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL25272620 | 0.78 | HDAC6 (0.62) | EGFRMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL14228915 | 0.78 | HDAC6 (0.62) | EGFRHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10767112-B2 | Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control | THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-08 | — | — | US | disclosed |
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-04-09 | — | — | US | disclosed |
| CN-106103348-B | The purposes of sulphur compound and selenium compound as the precursor of nano structural material | 哥伦比亚大学（纽约）理事会 | 2018-07-31 | — | — | CN | disclosed |
| US-20170369779-A1 | METHODS OF PRODUCING METAL SULFIDES, METAL SELENIDES, AND METAL SULFIDES/SELENIDES HAVING CONTROLLED ARCHITECTURES USING KINETIC CONTROL | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-12-28 | — | — | US | disclosed |
| CN-106103348-A | Sulphur compound and selenium compound are as the purposes of the precursor of nano structural material | 哥伦比亚大学（纽约）理事会 | 2016-11-09 | — | — | CN | disclosed |
| US-20160237345-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-08-18 | — | — | US | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-4199413-A | TIN SALT LAYER GIVES HIGH DENSITY IMAGES | MITA INDUSTRIAL COMPANY LIMITED (JP) | 1980-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | SCLY, TST, SOD1 | EGFR 4362/4885ERBB2 4533/4885MAPT 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.