Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721556 | 0.84 | KIF11 (0.59) | KDM4EALDH1A1HTTHPGDMAOA | |
| SCHEMBL14552258 | 0.79 | ALDH1A1 (0.68) | POLBTDP1GAAKDM4EALDH1A1 | |
| SCHEMBL4219929 | 0.78 | ALDH1A1 (0.61) | POLBTDP1GAAKDM4EALDH1A1 | |
| SCHEMBL14116119 | 0.78 | KIF11 (0.72) | POLBTDP1GAAKDM4EALDH1A1 | |
| SCHEMBL4010925 | 0.78 | TDP1 (0.64) | POLBTDP1GAAKDM4EALDH1A1 | |
| SCHEMBL25246575 | 0.78 | POLB (0.64) | POLBTDP1GAAKDM4EALDH1A1 | |
| SCHEMBL11981333 | 0.78 | POLB (1.00) | POLBTDP1GAAKDM4EALDH1A1 | |
| SCHEMBL5621445 | 0.78 | ALDH1A1 (0.73) | POLBTDP1GAAKDM4EALDH1A1 | |
| Acridone SCHEMBL29641306 | 0.77 | ALDH1A1 (1.00) | POLBTDP1GAAKDM4EALDH1A1 | |
| Acridone SCHEMBL29360611 | 0.77 | ALDH1A1 (1.00) | POLBTDP1GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |
| US-20020034828-A1 | NOVEL 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND THEIR PREPARATION | PIERCE CHEMICAL COMPANY | 2002-03-21 | — | — | US | disclosed |
| EP-1026156-A2 | Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation | PIERCE CHEMICAL COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |