Benzaldehyde

Benzaldehyde

SCHEMBL5458306

CN(C)C.O=Cc1ccccc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.78
CYP2A6 P11509 4/20 0.78
CYP2A13 Q16696 1/20 0.54
TSHR P16473 1/20 0.44
RELA Q04206 1/20 0.44
ALDH3A1 P30838 1/20 0.44
ALDH1A3 P47895 1/20 0.44
LMNA P02545 2/20 0.44
TRPA1 O75762 1/20 0.44
ALOX5 P09917 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 2/20 0.42
TYR P14679 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH5A1 P51649 1/20 0.42
ABAT P80404 1/20 0.42
UNG P13051 1/20 0.41
PPARG P37231 1/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzaldehyde SCHEMBL9075999 0.97 ALDH1A1 (0.74) ALDH1A1CYP2A6CYP2A13TSHRRELA
Benzaldehyde SCHEMBL27599293 0.91 ALDH1A1 (0.64) ALDH1A1CYP2A6CYP2A13TSHRRELA
Benzaldehyde SCHEMBL27957434 0.90 ALDH1A1 (0.70) ALDH1A1CYP2A6CYP2A13TSHRRELA
Benzaldehyde SCHEMBL11223342 0.90 ALDH1A1 (0.70) ALDH1A1CYP2A6CYP2A13TSHRRELA
Benzaldehyde SCHEMBL29291303 0.88 ALDH1A1 (0.88) ALDH1A1CYP2A6TSHRLMNATRPA1
Benzaldehyde SCHEMBL27780794 0.88 ALDH1A1 (0.88) ALDH1A1CYP2A6CYP2A13TSHRLMNA
Benzaldehyde SCHEMBL1330097 0.88
Benzaldehyde SCHEMBL9236967 0.88
Benzaldehyde SCHEMBL10051945 0.88
Benzaldehyde SCHEMBL22400699 0.88 ALDH1A1 (1.00) ALDH1A1CYP2A6TSHRLMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9987382-B2 Radiotracer compositions GE HEALTHCARE LIMITED (GB) 2018-06-05 US claimed
CN-104031139-B Be used for positron medicine of Alzheimer disease PET imaging and preparation method thereof THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XI'AN JIAOTONG UNIVERSITY (CN) 2016-05-04 CN claimed
CN-104800865-A Targeted positron tracer for realizing PET (Positron Emission Tomography) imaging of positive tumors for HER2 (Human Epidermal Growth Factor Receptor 2) expression, and preparation method of targeted positron tracer FIRST AFFILIATED HOSPITAL MEDICAL COLLEGE XI AN JIAOTONG UNIV 2015-07-29 CN claimed
CN-104031139-A Positive electron medicine for alzheimers disease PET (Positron Emission Tomography) imaging and preparation method of positive electron medicine FIRST AFFILIATED HOSPITAL MEDICAL COLLEGE XI AN JIAOTONG UNIV 2014-09-10 CN claimed
US-20070122341-A1 Benzylideneaniline derivatives and their radioisotope labeled compounds for binding and imaging of beta-amyloid plaques SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2007-05-31 US claimed
EP-2648767-B1 RADIOTRACER COMPOSITIONS GE HEALTHCARE LTD (GB) 2023-03-15 EP disclosed
US-20220202965-A1 RADIOTRACER COMPOSITIONS AND METHODS GE HEALTHCARE LTD (GB) 2022-06-30 US disclosed
EP-2761514-B1 METHOD OF OPERATING AN AUTOMATED RADIOPHARMACEUTICAL SYNTHESIZER GE HEALTHCARE LTD (GB) 2020-11-11 EP disclosed
US-10758887-B2 Method of operating an automated radiopharmaceutical synthesizer GE HEALTHCARE LIMITED (GB) 2020-09-01 US disclosed
CN-105848687-B Radiotracer compositions and methods 通用电气健康护理有限公司 2020-06-09 CN disclosed
US-20190001296-A1 METHOD OF OPERATING AN AUTOMATED RADIOPHARMACEUTICAL SYNTHESIZER GE HEALTHCARE LIMITED (GB) 2019-01-03 US disclosed
US-10029228-B2 Method of operating an automated radiopharmaceutical synthesizer GE HEALTHCARE LIMITED (GB) 2018-07-24 US disclosed
WO-2013048954-A1 METHOD OF OPERATING AN AUTOMATED RADIOPHARMACEUTICAL SYNTHESIZER GE HEALTHCARE LIMITED (GB) 2013-04-04 WO disclosed
WO-2012076697-A1 RADIOTRACER COMPOSITIONS GE HEALTHCARE LIMITED (GB) 2012-06-14 WO disclosed
CN-101065152-A Contrast agents targeting urokinase plasminogen activator receptor GE HEALTHCARE AS (NO) 2007-10-31 CN disclosed
US-20070122341-A1 Benzylideneaniline derivatives and their radioisotope labeled compounds for binding and imaging of beta-amyloid plaques SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2007-05-31 US disclosed
EP-0692982-A4 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS DU PONT MERCK PHARMA (US) 1998-03-11 EP disclosed
CN-1122577-A Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders DU PONT MERCK PHARMA (US) 1996-05-15 CN disclosed
EP-0692982-A1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-24 EP disclosed
WO-1994022494-A1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202965-A1 RADIOTRACER COMPOSITIONS AND METHODS MET, METTL14, MEN1 ALDH1A1 4112/4885CYP2A6 4220/4885CYP2A13 4040/4885
US-20070122341-A1 Benzylideneaniline derivatives and their radioisotope labeled compounds for binding and imaging of beta-amyloid plaques APP, BACE1, APBA1 ALDH1A1 2630/4885CYP2A6 1888/4885CYP2A13 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.