Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.58 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549910 | 0.88 | NPC1 (0.50) | NAMPTEPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5473484 | 0.83 | NAMPT (0.62) | NAMPTWNT3APDK4CDK7CDK13 | |
| SCHEMBL5465678 | 0.81 | ESR2 (0.53) | NAMPTEPHX2NPC1RAB9ACASP3 | |
| SCHEMBL5456796 | 0.81 | NAMPT (0.56) | NAMPTEPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5465641 | 0.80 | NAMPT (0.58) | NAMPTEPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5457909 | 0.79 | MAPT (0.52) | NAMPTEPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5458325 | 0.79 | NAMPT (0.64) | NAMPTPDK4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22325022 | 0.78 | NAMPT (0.71) | NAMPTWNT3APDK4NPC1RAB9A | |
| SCHEMBL31488923 | 0.78 | NAMPT (0.68) | NAMPTPDK4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3987919 | 0.78 | NAMPT (0.59) | NAMPTWNT3APDK4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | NAMPT 324/4885WNT3A 3010/4885EPHX2 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.