Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.64 |
| ▸ | GRM5 | P41594 | 2/20 | 0.55 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453589 | 0.89 | NAMPT (0.57) | NAMPTGRM5GRM1RAB9AMAPT | |
| SCHEMBL5465684 | 0.87 | NAMPT (0.65) | NAMPTGRM5GRM1RAB9ANPC1 | |
| SCHEMBL5466920 | 0.87 | RAB9A (0.56) | NAMPTRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5473484 | 0.85 | NAMPT (0.62) | NAMPTGRM5GRM1PDK4ALDH1A1 | |
| SCHEMBL22325022 | 0.80 | NAMPT (0.71) | NAMPTGRM5GRM1RAB9ANPC1 | |
| SCHEMBL5460804 | 0.80 | MAPT (0.68) | NAMPTRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL3317600 | 0.79 | NAMPT (0.54) | NAMPTGRM5GRM1PDK4 | |
| SCHEMBL5460878 | 0.79 | NPC1 (0.62) | NAMPTRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5458375 | 0.79 | NAMPT (0.58) | NAMPTGRM5GRM1RAB9ANPC1 | |
| SCHEMBL5456870 | 0.78 | NAMPT (0.64) | NAMPTRAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | NAMPT 324/4885GRM5 2380/4885GRM1 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.