Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458680 | 0.87 | HDAC6 (0.56) | HDAC6DAPK1FGFR1FGFR4ADORA2A | |
| SCHEMBL5458724 | 0.85 | YTHDC1 (0.61) | HDAC6DAPK1FGFR1FGFR4ADORA2A | |
| SCHEMBL3394097 | 0.84 | HDAC6 (0.60) | HDAC6ADORA2AHSD17B13YTHDC1 | |
| SCHEMBL5042088 | 0.83 | SLC29A1 (0.56) | DAPK1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL5467475 | 0.80 | ADORA2A (0.57) | ADORA2A | |
| SCHEMBL30984022 | 0.79 | ADORA2A (0.70) | HDAC6DAPK1FGFR1FGFR4ADORA2A | |
| SCHEMBL2980291 | 0.79 | ADORA2A (0.70) | HDAC6DAPK1FGFR1FGFR4ADORA2A | |
| SCHEMBL5451886 | 0.75 | HDAC6 (0.63) | HDAC6FGFR1FGFR4ADORA2API4KA | |
| SCHEMBL5045749 | 0.74 | SLC29A1 (0.64) | SLC29A1 | |
| SCHEMBL5458877 | 0.74 | HDAC6 (0.60) | HDAC6FGFR1FGFR4ADORA2API4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | HDAC6 4066/4885DAPK1 2173/4885FGFR1 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.