SCHEMBL5458735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5456024	0.81	ALDH1A1 (0.57)	NPC1RAB9ASMN1; SMN2LMNATP53
	SCHEMBL5470441	0.77	MAPT (0.70)	NPC1RAB9ATP53CYP1A2CYP3A4
	SCHEMBL2360807	0.76	CACNA1D (0.52)	SCN4ATP53CYP1A2CYP3A4CYP2C9
	SCHEMBL4401590	0.76	MEN1 (0.54)	NPC1RAB9ASMN1; SMN2LMNATP53
	Hydrochloric Acid SCHEMBL5809665	0.75	BRD4 (0.41)	NPC1RAB9ASMN1; SMN2SCN4ASCN9A
	SCHEMBL2857719	0.74	MEN1 (0.44)	NPC1RAB9AHSD17B10MAPTALDH1A1
	Hydrochloric Acid SCHEMBL5809663	0.73	ALDH1A1 (0.48)	NPC1RAB9ASMN1; SMN2TP53CYP3A4
	SCHEMBL2734327	0.73	KDM4E (0.52)	NPC1RAB9ASMN1; SMN2LMNATP53
	SCHEMBL30914192	0.73	KMT2A (0.56)	NPC1RAB9ASMN1; SMN2LMNATP53
	SCHEMBL23361964	0.72	POLB (0.69)	SMN1; SMN2BRD4MAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.