Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456024 | 0.82 | ALDH1A1 (0.57) | MAPTACSS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5458735 | 0.77 | NPC1 (0.49) | MAPTACSS2ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL23490723 | 0.76 | NPC1 (0.46) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL13618551 | 0.74 | RAF1 (0.44) | MAPTALDH1A1PPARG | |
| SCHEMBL2734327 | 0.74 | KDM4E (0.52) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6623126 | 0.73 | KDM4E (0.51) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL11823 | 0.73 | TLR8 (0.58) | MAPTACSS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8253380 | 0.73 | SIRT2 (0.52) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11711378 | 0.72 | HTT (0.53) | MAPTACSS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL18675058 | 0.72 | ACSS2 (1.00) | MAPTACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | MAPT 2918/4885ACSS2 392/4885ALDH1A1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.