Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456431 | 0.86 | CYP1A2 (0.50) | ALDH1A1POLBHTTSMN1; SMN2ACSS2 | |
| SCHEMBL5470441 | 0.82 | MAPT (0.70) | ALDH1A1POLBHTTACSS2MAPT | |
| SCHEMBL5458735 | 0.81 | NPC1 (0.49) | ALDH1A1POLBHTTSMN1; SMN2ACSS2 | |
| SCHEMBL14344232 | 0.81 | MAPT (0.69) | ALDH1A1SMN1; SMN2ACSS2TDP1MAPT | |
| SCHEMBL2361751 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBHTTSMN1; SMN2FGFR1 | |
| SCHEMBL25443596 | 0.79 | ALDH1A1 (0.55) | ALDH1A1POLBHTTSMN1; SMN2ACSS2 | |
| SCHEMBL3965377 | 0.79 | ALDH1A1 (0.55) | ALDH1A1POLBHTTSMN1; SMN2ACSS2 | |
| SCHEMBL1104364 | 0.79 | ALDH1A1 (0.55) | ALDH1A1POLBHTTSMN1; SMN2ACSS2 | |
| Hydrochloric Acid SCHEMBL7236753 | 0.79 | CCR1 (0.46) | ALDH1A1POLBHTTSMN1; SMN2ACSS2 | |
| SCHEMBL28370090 | 0.79 | CLK4 (0.41) | ALDH1A1POLBHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | ALDH1A1 39/4885POLB 2088/4885HTT 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.