Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577986 | 0.84 | BCHE (0.49) | PDE4DPDE10ABCHECOXFA4MALT1 | |
| SCHEMBL546699 | 0.78 | HSP90AA1 (0.42) | PDE4DBCHECOXFA4CYSLTR2CYSLTR1 | |
| SCHEMBL546720 | 0.78 | HSP90AA1 (0.42) | PDE4DBCHECOXFA4CYSLTR2CYSLTR1 | |
| SCHEMBL13993758 | 0.75 | BCHE (0.44) | PDE4DPDE10ABCHECOXFA4MALT1 | |
| SCHEMBL13993749 | 0.73 | COXFA4 (0.46) | PDE4DPDE10ABCHECOXFA4MALT1 | |
| SCHEMBL13993755 | 0.73 | COXFA4 (0.48) | PDE4DPDE10ABCHECOXFA4MALT1 | |
| SCHEMBL546729 | 0.73 | BCHE (0.65) | PDE4DPDE10ABCHECOXFA4OPRM1 | |
| SCHEMBL7994834 | 0.72 | SMPD1 (0.54) | PDE4BHTR2A | |
| SCHEMBL13993759 | 0.72 | BCHE (0.43) | PDE4DPDE10ABCHECOXFA4MALT1 | |
| SCHEMBL10508118 | 0.72 | TLR3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46228-E1 | Pigmentation-regulating compounds | LIPOTEC, S.A. (ES) | 2016-12-06 | — | — | US | disclosed |
| EP-2159223-B1 | 6 -ACYLOXY- 7-METH0XY- 2, 2 -DIMETHYLCHROMANE COMPOUNDS AND THEIR USE AS PIGMENTATION-REGULATORS | LIPOTEC SA (ES) | 2014-03-12 | — | — | EP | disclosed |
| US-8110207-B2 | Pigmentation-regulating compounds | LIPOTEC, S.A. (ES) | 2012-02-07 | — | — | US | disclosed |
| US-20100247587-A1 | PIGMENTATION-REGULATING COMPOUNDS | LIPOTEC, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |
| EP-2159223-A2 | 6 -ACYLOXY- 7-METH0XY- 2, 2 -DIMETHYLCHROMANE COMPOUNDS AND THEIR USE AS PIGMENTATION-REGULATORS | Lipotec, S.A. (ES) | 2010-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247587-A1 | PIGMENTATION-REGULATING COMPOUNDS | TYR, MC1R, MITF | PDE4B 3851/4885PDE4D 3777/4885PDE10A 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.