Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546699 | 1.00 | HSP90AA1 (0.42) | HSP90AA1BCHECOXFA4CYSLTR2CYSLTR1 | |
| SCHEMBL29400720 | 1.00 | HSP90AA1 (0.42) | HSP90AA1BCHECOXFA4CYSLTR2CYSLTR1 | |
| SCHEMBL11156631 | 0.80 | BCHE (0.44) | HSP90AA1BCHECOXFA4CYSLTR2CYSLTR1 | |
| SCHEMBL545891 | 0.78 | PDE4B (0.43) | BCHECOXFA4CYSLTR2CYSLTR1PDE4D | |
| SCHEMBL18270705 | 0.77 | CTSB (0.46) | COXFA4 | |
| SCHEMBL546770 | 0.76 | ALDH1A1 (0.48) | HSP90AA1COXFA4 | |
| SCHEMBL13993752 | 0.76 | PDE10A (0.42) | HSP90AA1BCHECOXFA4POLBKMT2A | |
| SCHEMBL577986 | 0.73 | BCHE (0.49) | HSP90AA1BCHECOXFA4POLBMAPT | |
| SCHEMBL29401664 | 0.71 | BCHE (0.65) | BCHECOXFA4POLBNFKB1NFKB2 | |
| SCHEMBL13993749 | 0.71 | COXFA4 (0.46) | HSP90AA1BCHECOXFA4POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46228-E1 | Pigmentation-regulating compounds | LIPOTEC, S.A. (ES) | 2016-12-06 | — | — | US | disclosed |
| EP-2159223-B1 | 6 -ACYLOXY- 7-METH0XY- 2, 2 -DIMETHYLCHROMANE COMPOUNDS AND THEIR USE AS PIGMENTATION-REGULATORS | LIPOTEC SA (ES) | 2014-03-12 | — | — | EP | disclosed |
| US-8110207-B2 | Pigmentation-regulating compounds | LIPOTEC, S.A. (ES) | 2012-02-07 | — | — | US | disclosed |
| US-20100247587-A1 | PIGMENTATION-REGULATING COMPOUNDS | LIPOTEC, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |
| EP-2159223-A2 | 6 -ACYLOXY- 7-METH0XY- 2, 2 -DIMETHYLCHROMANE COMPOUNDS AND THEIR USE AS PIGMENTATION-REGULATORS | Lipotec, S.A. (ES) | 2010-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247587-A1 | PIGMENTATION-REGULATING COMPOUNDS | TYR, MC1R, MITF | HSP90AA1 3726/4885BCHE 3631/4885COXFA4 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.