SCHEMBL5459128

SCHEMBL5459128

CCCCB(Cl)CCCC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.47
TSHR P16473 5/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
THRB P10828 1/20 0.38
ALDH1A1 P00352 4/20 0.36
TP53 P04637 1/20 0.36
PCSK9 Q8NBP7 1/20 0.32
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6748891 0.90 TSHR (0.44) ANPEPTSHRLMNATDP1THRB
SCHEMBL6741851 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL6741870 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL6743258 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL11594245 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL3888791 0.79
SCHEMBL6741874 0.77
SCHEMBL7788025 0.73 ANPEP (0.43) ANPEPTSHRLMNATDP1THRB
Hexane SCHEMBL2922117 0.72 TSHR (0.58) TSHRLMNATDP1THRBALDH1A1
SCHEMBL1237 0.69 ANPEP (0.53) ANPEPTSHRLMNATDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030207757-A1 Catalyst composition comprising metallocene compound having bulky cycloalkyl-substituted cyclopentadienyl ligand, and process for olefin polymerization using the same DAELIM INDUSTRIES CO., LTD. (KR) 2003-11-06 US claimed
US-8557935-B2 Bimetallic catalyst, method of polymerization and bimodal polyolefins therefrom UNIVATION TECHNOLOGIES, LLC (US) 2013-10-15 US disclosed
US-20120271015-A1 Bimetallic Catalyst, Method of Polymerization and Bimodal Polyolefins Therefrom UNIVATION TECHNOLOGIES, LLC (US) 2012-10-25 US disclosed
US-8222176-B2 Bimetallic catalyst, method of polymerization and bimodal polyolefins therefrom UNIVATION TECHNOLOGIES, LLC (US) 2012-07-17 US disclosed
CN-1912008-B Resin composition, protective film of color filter and method for forming the same JSR CORP 2012-05-23 CN disclosed
EP-1620472-B1 METHODS OF POLYMERIZING OLEFIN MONOMERS WITH MIXED CATALYST SYSTEMS UNIVATION TECH LLC (US) 2007-12-12 EP disclosed
US-20070123414-A1 Bimetallic catalyst, method of polymerization and bimodal polyolefins therefrom UNIVATION TECHNOLOGIES, LLC (US) 2007-05-31 US disclosed
CN-1912008-A Resin composition, protection film of color filter and forming method thereof JSR CORP (JP) 2007-02-14 CN disclosed
US-7172987-B2 Bimetallic catalyst, method of polymerization and bimodal polyolefins therefrom UNIVATION TECHNOLOGIES, LLC (US) 2007-02-06 US disclosed
CN-1264869-C Modified particles, carrier prepared therefrom, olefin polymerization catalyst component prepared therefrom, olefin polymerization catalyst prepared therefrom, and process for preparing olefin polymer SUMITOMO CHEMICAL CO (JP) 2006-07-19 CN disclosed
US-4330646-A Polymerization of an α-olefin ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-05-18 US disclosed
EP-0044835-A1 CATALYSED ALTERNATING COPOLYMERISATION AND PRODUCT NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1982-02-03 EP disclosed
WO-1981001289-A1 CATALYSED ALTERNATING COPOLYMERISATION AND PRODUCT BAMFORD C 1981-05-14 WO disclosed
US-4161571-A GELATION INHIBITORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-07-17 US disclosed
US-4121032-A Process for preparing alternating copolymer of conjugated vinyl compound and olefinic unsaturated compound with oxygen and boron compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-10-17 US disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-4080493-A POLYBUTADIENE, POLYISOPRENE, GELATION INHIBITOR SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US disclosed
US-4054612-A HOMO- OR COPOLYMERIZATION OF BUTADIENE, CATALYTIC SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-10-18 US disclosed
US-4052473-A OF ISOPRENE, NICKEL-ALKYLAMUMIN HALIDE CONTAINING CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-10-04 US disclosed
US-3989882-A Process for preparing an alternating copolymer of a conjugated vinyl compound and an olefinic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-02 US disclosed