SCHEMBL6743258

SCHEMBL6743258

CCCCCCCB(Cl)CCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 4/20 0.45
DNM1 Q05193 6/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6741851 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11594245 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6741870 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6748891 0.97 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL5459128 0.87 ANPEP (0.47) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL733804 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6746369 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11229821 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9776618 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
Heptane SCHEMBL6917596 0.79 TSHR (0.67) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696380-B2 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2004-02-24 US disclosed
US-6677410-B2 COORDINATION CATALYSTS EASTMAN CHEMICAL COMPANY 2004-01-13 US disclosed
US-20030004285-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2003-01-02 US disclosed
US-6465383-B2 COORDINATION CATALYST EASTMAN CHEMICAL COMPANY 2002-10-15 US disclosed
US-20010051587-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-12-13 US disclosed
US-20010031841-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-10-18 US disclosed
US-20010029286-A1 Procatalysts, catalyst systems, and use in OLEFIN polymerization EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE 2001-10-11 US disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
WO-2001051526-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051527-A1 PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051528-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051529-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed