Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5292811 | 0.83 | HDAC8 (0.64) | MTNR1AMTNR1BHDAC8HDAC6PLK1 | |
| Acrylic Acid Methyl Ester SCHEMBL28106400 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BHDAC8HDAC6PLK1 | |
| SCHEMBL3245346 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BHDAC8HDAC6PLK1 | |
| SCHEMBL6018154 | 0.79 | PLK1 (0.56) | MTNR1AMTNR1BHDAC8HDAC6PLK1 | |
| SCHEMBL28312715 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1BHDAC8HDAC6PLK1 | |
| SCHEMBL1086540 | 0.77 | GRIN2D (0.53) | MTNR1AMTNR1BHDAC8HDAC6PLK1 | |
| SCHEMBL5651919 | 0.77 | NR4A1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6ALDH1A1 | |
| SCHEMBL15913822 | 0.76 | MAPT (0.56) | MTNR1AMTNR1BHDAC8HDAC6ALDH1A1 | |
| SCHEMBL29489353 | 0.76 | MAPT (0.56) | MTNR1AMTNR1BHDAC8HDAC6ALDH1A1 | |
| Cyclopropane SCHEMBL11853273 | 0.76 | HDAC8 (0.51) | MTNR1AMTNR1BHDAC8HDAC6PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103319712-A | Triazine ring-containing polymer and film-forming composition comprising same | NISSAN CHEMICAL IND LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-102731387-A | A salt for dye | SUMITOMO CHEMICAL CO | 2012-10-17 | — | — | CN | disclosed |
| CN-102459415-A | Triazine ring-containing polymer and film-forming composition containing same | NISSAN CHEMICAL IND LTD | 2012-05-16 | — | — | CN | disclosed |
| US-20070112016-A1 | Novel 3-spirocyclic indolyl derivatives useful as ORL-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112016-A1 | Novel 3-spirocyclic indolyl derivatives useful as ORL-1 receptor modulators | OXER1, OGFRL1, NR1H2 | MTNR1A 82/4885MTNR1B 114/4885HDAC8 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.