Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459447 | 0.94 | THRB (0.42) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5452963 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5353717 | 0.89 | KDM4E (0.43) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5354114 | 0.89 | KDM4E (0.42) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5346954 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5474076 | 0.87 | KDM4E (0.42) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5361936 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5464589 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5367673 | 0.85 | THRB (0.45) | ALDH1A1KDM4EHPGDDRD3LMNA | |
| SCHEMBL5372559 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDDRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287699-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | ALDH1A1 1759/4885KDM4E 3960/4885HPGD 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.