Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | YTHDC1 | Q96MU7 | 8/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465713 | 0.88 | P2RX7 (0.56) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL13596788 | 0.85 | HDAC6 (0.57) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL5461215 | 0.85 | HDAC6 (0.60) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL183057 | 0.85 | YTHDC1 (0.68) | HDAC1HDAC2HDAC8YTHDC1P2RX7 | |
| SCHEMBL30898278 | 0.85 | YTHDC1 (0.68) | HDAC1HDAC2HDAC8YTHDC1P2RX7 | |
| SCHEMBL3821565 | 0.85 | YTHDC1 (0.57) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL5471560 | 0.83 | YTHDC1 (0.55) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL5787827 | 0.82 | ADORA2A (0.53) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL5460319 | 0.82 | YTHDC1 (0.63) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL15921464 | 0.82 | ADORA2A (0.52) | HDAC6HDAC1HDAC4HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903987-B1 | PHOSPHOLIPID DRUG ANALOGS | UROGEN PHARMA LTD (IL) | 2017-09-20 | — | — | EP | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | HDAC6 4066/4885HDAC1 4234/4885HDAC4 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.