Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | CASP6 | P55212 | 1/20 | 0.70 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CDC42 | P60953 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455548 | 0.90 | PRMT5 (0.72) | GAACASP6PRMT5CDC42SIRT1 | |
| SCHEMBL4187019 | 0.89 | GAA (0.72) | GAACASP6PRMT5CDC42SIRT1 | |
| SCHEMBL4165396 | 0.89 | GAA (0.66) | GAACASP6PRMT5MAPTALOX15 | |
| SCHEMBL5460613 | 0.88 | GAA (0.68) | GAACASP6PRMT5CDC42SIRT1 | |
| Hydrochloric Acid SCHEMBL4158259 | 0.88 | GAA (0.74) | GAACASP6PRMT5CDC42SIRT1 | |
| SCHEMBL5461938 | 0.88 | GAA (0.70) | GAACASP6PRMT5MAPTALOX15 | |
| SCHEMBL31497434 | 0.87 | ALOX15 (0.52) | GAACASP6PRMT5MAPTALOX15 | |
| SCHEMBL31497423 | 0.85 | MAPT (0.52) | GAACASP6PRMT5MAPTALOX15 | |
| SCHEMBL31497463 | 0.84 | PRMT5 (0.57) | GAACASP6PRMT5MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL7482679 | 0.84 | GAA (0.81) | GAACASP6PRMT5MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | MAVS, SARS1, ZC3HAV1 | GAA 1417/4885CASP6 3264/4885PRMT5 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.