Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455538 | 0.83 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL5455534 | 0.82 | TUBB4A (0.49) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL27503313 | 0.81 | CYP17A1 (0.60) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL5457223 | 0.81 | MAPK1 (0.51) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL26260092 | 0.78 | NPC1 (0.60) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL5468292 | 0.77 | CYP19A1 (0.52) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL5459676 | 0.77 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL13781462 | 0.77 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL12381484 | 0.76 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1CYP17A1POLB | |
| SCHEMBL5457794 | 0.75 | POLB (0.55) | CYP11B1CYP11B2CYP19A1CYP17A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39663-E1 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes | APPLERA CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1196640-B1 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1196640-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | Applera Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001057264-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-6221604-B1 | CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE | PE CORPORATION | 2001-04-24 | — | — | US | disclosed |