Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546112 | 0.86 | TACR1 (0.41) | TACR1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL806193 | 0.76 | NOS1 (0.49) | TACR1NOS3NOS1NOS2 | |
| SCHEMBL1205533 | 0.76 | MAOA (0.49) | MEN1HTTKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL787716 | 0.75 | NOS1 (0.50) | TACR1NOS3NOS1NOS2 | |
| SCHEMBL1845384 | 0.75 | MEN1 (0.46) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL5428175 | 0.74 | TACR1 (0.52) | TACR1 | |
| SCHEMBL27385426 | 0.74 | TACR1 (0.42) | TACR1MEN1KMT2A | |
| SCHEMBL14257961 | 0.73 | TACR1 (0.42) | TACR1KMT2A | |
| SCHEMBL28560207 | 0.72 | EPHX1 (0.39) | TACR1 | |
| SCHEMBL545287 | 0.72 | NR1H2 (0.44) | MEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110687-B2 | Bicyclic compounds with kinase inhibitory activity | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-02-07 | — | — | US | disclosed |