Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447120 | 0.87 | PDE10A (0.44) | CSNK1A1CSNK1DPDE10AERN1KDM4E | |
| SCHEMBL5444073 | 0.85 | CSNK1A1 (0.41) | CSNK1A1CSNK1DPDE10AKDM4EKDR | |
| SCHEMBL5449706 | 0.83 | RIPK1 (0.39) | CSNK1A1CSNK1DPDE10AKDR | |
| SCHEMBL5450107 | 0.83 | CBFB (0.37) | CSNK1A1CSNK1DPDE10AKDR | |
| SCHEMBL5459667 | 0.69 | SYK (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19CSNK1A1 | |
| SCHEMBL5447392 | 0.68 | CSNK1A1 (0.42) | CSNK1A1CSNK1DPDE10AKDM4EIDH2 | |
| SCHEMBL921952 | 0.67 | — | — | |
| SCHEMBL921631 | 0.66 | MAOB (0.42) | — | |
| SCHEMBL2489990 | 0.66 | PDE10A (0.61) | PDE10A | |
| SCHEMBL5767341 | 0.64 | PDE10A (0.38) | CYP1A2CYP3A4CYP2D6CETPCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | TIE1, KDR, FLT1 | CYP1A2 2260/4885CYP3A4 3875/4885CYP2D6 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.