Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466688 | 0.82 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL5451931 | 0.82 | NR3C1 (0.36) | NR3C1PGRLMNAHTT | |
| SCHEMBL5462980 | 0.80 | NR3C1 (0.55) | NR3C1PGRGAAHTT | |
| SCHEMBL5452611 | 0.77 | NR3C1 (0.42) | NR3C1PGR | |
| SCHEMBL5458893 | 0.77 | NTRK1 (0.31) | LMNAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1261870 | 0.73 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL14421975 | 0.73 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL1261867 | 0.73 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL14422034 | 0.73 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL1261475 | 0.73 | NR3C1 (0.64) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108714-A2 | TETRAHYDRONAPHTHALENE DERIVATIVES METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-10-19 | — | — | WO | claimed |
| US-20070015750-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAEURLE STEFAN | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015750-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | DHPS, TNF, PTGES | NR3C1 676/4885PGR 3316/4885LMNA 4201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.