Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 17/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528796 | 0.93 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL5528801 | 0.93 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL3939325 | 0.85 | MCHR1 (0.61) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL3939323 | 0.85 | MCHR1 (0.61) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL5463167 | 0.85 | PTPN11 (0.49) | NPY5RCDC7DAPK3JAK2ROCK2 | |
| SCHEMBL5463157 | 0.85 | PTPN11 (0.49) | NPY5RCDC7DAPK3JAK2ROCK2 | |
| SCHEMBL5463162 | 0.85 | PTPN11 (0.49) | NPY5RCDC7DAPK3JAK2ROCK2 | |
| SCHEMBL4030769 | 0.85 | MCHR1 (0.60) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL3943726 | 0.84 | MCHR1 (0.60) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL30454842 | 0.83 | MCHR1 (0.67) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185119-A1 | Therapeutic agents II | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185119-A1 | Therapeutic agents II | HTT, ACHE, GPR119 | MCHR1 968/4885ADRA2A 702/4885NPY5R 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.