Sugi Predict

Sugi Predict / Compounds / SCHEMBL5459905

SCHEMBL5459905

SCHEMBL5459905

Cc1c(O)c2ccccc2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 1.00
▸ CA12 O43570 1/20 0.62
▸ CA9 Q16790 1/20 0.62
▸ NQO1 P15559 5/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ CYP2C9 P11712 2/20 0.61
▸ MEN1 O00255 1/20 0.61
▸ ABCB11 O95342 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ TP53 P04637 1/20 0.61
▸ CYP1A2 P05177 1/20 0.61
▸ CYP3A4 P08684 1/20 0.61
▸ TSHR P16473 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ CYP2C19 P33261 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ PDE4D Q08499 1/20 0.61
▸ PCSK7 Q16549 1/20 0.61
▸ GPR35 Q9HC97 1/20 0.61
▸ MAPT P10636 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29695571 1.00 KDM4E (1.00) KDM4ECA12CA9NQO1ALDH1A1
SCHEMBL30153359 0.85 KDM4E (0.73) KDM4ECA12CA9NQO1ALDH1A1
SCHEMBL5532851 0.85 KDM4E (0.73) KDM4ECA12CA9NQO1ALDH1A1
SCHEMBL2450078 0.84 KDM4E (0.71) KDM4ECA12CA9ALDH1A1MEN1
SCHEMBL29379994 0.82 KDM4E (0.69) KDM4ECA12CA9NQO1ALDH1A1
SCHEMBL7737431 0.82 KDM4E (0.69) KDM4ECA12CA9NQO1ALDH1A1
SCHEMBL29872 0.82 KDM4E (0.69) KDM4ECA12CA9NQO1ALDH1A1
Hydrochloric Acid SCHEMBL8701572 0.80 KDM4E (0.67) KDM4ECA12CA9NQO1ALDH1A1
Isopropyl Alcohol SCHEMBL11096119 0.79 KDM4E (0.66) KDM4ECA12CA9NQO1CYP2C9
Acetic Acid SCHEMBL15653002 0.79 KDM4E (0.66) KDM4ECA12CA9ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3589743-B1 RECOVERY MEDIUM FOR DETECTION OF MICROORGANISMS BY FLUORESCENCE AMERICAN STERILIZER CO (US) 2023-06-21 — — EP disclosed
US-10369130-B2 Antibacterial compounds AZIEN DE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 2019-08-06 — — US disclosed
US-10369130-B2 Antibacterial compounds AZIEN DE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 2019-08-06 — — US disclosed
CN-106749296-B Asymmetric synthesis method of chiral furo [3,2-c ] chromene compound 浙江工业大学 2019-04-09 — — CN disclosed
CN-105263412-B Correction of osmotic pressure variations in chemo-optical sensor sites 皇家飞利浦有限公司 2019-03-08 — — CN disclosed
WO-2018160449-A1 RECOVERY MEDIUM FOR DETECTION OF MICROORGANISMS BY FLUORESCENCE AMERICAN STERILIZER COMPANY (US) 2018-09-07 — — WO disclosed
US-20180245122-A1 RECOVERY MEDIUM FOR DETECTION OF MICROORGANISMS BY FLUORESCENCE AMERICAN STERILIZER COMPANY 2018-08-30 — — US disclosed
US-20170368017-A1 ANTIBACTERIAL COMPOUNDS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2017-12-28 — — US disclosed
US-20170368017-A1 ANTIBACTERIAL COMPOUNDS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2017-12-28 — — US disclosed
EP-3233826-A1 NEW ANTIBACTERIAL COMPOUNDS Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) 2017-10-25 — — EP disclosed
WO-2001014370-A1 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF REPHARTOX (NL) 2001-03-01 — — WO disclosed
US-5994065-A BLOCKING NON-SPECIFIC SITES ON A SOLID SUPPORT HAVING IMMOBILIZED TARGET LIGANDS COMPRISING NUCLEIC ACIDS BY REACTING WITH AN ACYCLIC OR HETEROCYCLIC CARBOXYLIC ANHYDRIDE; CONTACTING WITH A PROBE RAPIGENE, INC. (US) 1999-11-30 — — US disclosed
EP-0862655-A1 METHODS FOR PREPARING SOLID SUPPORTS FOR HYBRIDIZATION AND REDUCING NON-SPECIFIC BACKGROUND DARWIN MOLECULAR CORPORATION (US) 1998-09-09 — — EP disclosed
WO-1997014815-A1 METHODS FOR PREPARING SOLID SUPPORTS FOR HYBRIDIZATION AND REDUCING NON-SPECIFIC BACKGROUND DARWIN MOLECULAR CORP. (US) 1997-04-24 — — WO disclosed
EP-0539515-A4 — — 1995-04-26 — — EP disclosed
US-5393672-A Using benzyl alcohol and derivatives MICROPROBE CORPORATION (US) 1995-02-28 — — US disclosed
EP-0539515-A1 NON-CORROSIVE COMPOSITION AND METHODS USEFUL FOR THE EXTRACTION OF NUCLEIC ACIDS MICROPROBE CORPORATION (US) 1993-05-05 — — EP disclosed
WO-1992000983-A1 NON-CORROSIVE COMPOSITION AND METHODS USEFUL FOR THE EXTRACTION OF NUCLEIC ACIDS MICROPROBE CORPORATION (US) 1992-01-23 — — WO disclosed
US-4918200-A Chromogenic and fluorogenic silanes and using the same HULS AMERICA INC. (US) 1990-04-17 — — US disclosed
US-4230850-A HYPOTENSIVE AGENTS, VASODILATION LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1980-10-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10369130-B2 Antibacterial compounds MRPL21, CLPP, NRDC KDM4E 4034/4885CA12 4771/4885CA9 4016/4885
US-20170368017-A1 ANTIBACTERIAL COMPOUNDS MRPL21, CLPP, NRDC KDM4E 4034/4885CA12 4771/4885CA9 4016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.