Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.78 |
| ▸ | HTR1A | P08908 | 4/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9654109 | 0.99 | NISCH (0.76) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3962998 | 0.86 | NISCH (0.74) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9655504 | 0.85 | NISCH (0.64) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9655718 | 0.85 | HTR1A (0.72) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9654820 | 0.85 | NISCH (0.64) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9654911 | 0.85 | NISCH (0.72) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9653926 | 0.83 | NISCH (0.76) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9655719 | 0.82 | NISCH (0.62) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9655510 | 0.81 | NISCH (0.60) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9652303 | 0.81 | LMNA (0.77) | NISCHHTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049797-A2 | Anthelminticum containing 2-(2,3-dimethyl-phenoxy-methyl)-2-imidazoline | BAYER AG (DE) | 1982-04-21 | — | — | EP | claimed |
| US-8110593-B2 | Phenoxymethyl imidazoline derivatives and their use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-8110593-B2 | Phenoxymethyl imidazoline derivatives and their use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-8110593-B2 | Phenoxymethyl imidazoline derivatives and their use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100120881-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120881-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120881-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| CN-101627016-A | Compound (I) | SYNGENTA PARTICIPATIONS AG | 2010-01-13 | — | — | CN | disclosed |
| EP-2117310-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008098657-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-21 | — | — | WO | disclosed |
| EP-1958507-A1 | Chemical compounds | Syngeta Participations AG (CH) | 2008-08-20 | — | — | EP | disclosed |
| EP-1958507-A1 | Chemical compounds | Syngeta Participations AG (CH) | 2008-08-20 | — | — | EP | disclosed |
| US-4414223-A | MITICIDWS | BURROUGHS WELLCOME CO. (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0049797-A3 | ANTHELMINTICUM CONTAINING 2-(2,3-DIMETHYL-PHENOXY-METHYL)-2-IMIDAZOLINE | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0049797-A2 | Anthelminticum containing 2-(2,3-dimethyl-phenoxy-methyl)-2-imidazoline | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
| EP-0049797-A2 | Anthelminticum containing 2-(2,3-dimethyl-phenoxy-methyl)-2-imidazoline | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
| US-4228175-A | Bis-(phenoxyalkyl-2-imidazolin)-1,1-sulfides, process for their manufacture, compositions which contain these sulfides as active component and use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4226876-A | MITICIDES | BURROUGHS WELLCOME CO. (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0008565-A1 | Bis-(phenoxy-alkyl-2-imidazoline)-1,1'-sulfides, process for their preparation, agents containing these sulfides as active components, and their use in combating pesticides | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120881-A1 | CHEMICAL COMPOUNDS | AADAC, ACHE, ATL3 | NISCH 4/4885HTR1A 3389/4885ADRA2A 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.