Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473783 | 0.87 | NR3C1 (0.42) | NR3C1PGR | |
| SCHEMBL5471686 | 0.82 | TRPV1 (0.36) | — | |
| SCHEMBL5460516 | 0.81 | NR3C1 (0.43) | NR3C1PGR | |
| SCHEMBL5462988 | 0.80 | NR3C1 (0.39) | NR3C1PGRMEN1KMT2A | |
| SCHEMBL5451945 | 0.79 | NR3C1 (0.35) | NR3C1 | |
| SCHEMBL5460242 | 0.79 | NR3C1 (0.44) | NR3C1PGRUSP1WDR48KDM4E | |
| SCHEMBL5463946 | 0.78 | NR3C1 (0.40) | NR3C1PGRMEN1KMT2AGAA | |
| SCHEMBL3532206 | 0.76 | NR3C1 (0.56) | NR3C1PGRKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3532207 | 0.76 | NR3C1 (0.56) | NR3C1PGRKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5458960 | 0.71 | NR3C1 (0.41) | NR3C1PGRUSP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015750-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAEURLE STEFAN | 2007-01-18 | — | — | US | disclosed |
| WO-2006108714-A2 | TETRAHYDRONAPHTHALENE DERIVATIVES METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015750-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | DHPS, TNF, PTGES | NR3C1 676/4885PGR 3316/4885USP1 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.