SCHEMBL5463134

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5335284	0.81	DRD2 (0.55)	CHRM1CHRM2CHRM4HTR1ACHRM5
	SCHEMBL5345306	0.73	CHRM1 (0.61)	ALDH1A1SMN1; SMN2HPGDRAB9ANPC1
	SCHEMBL29594271	0.72	LOXL2 (0.56)	SMN1; SMN2LMNAMAPTHTR1ADRD2
	SCHEMBL1287509	0.72	LOXL2 (0.56)	SMN1; SMN2LMNAMAPTHTR1ADRD2
	SCHEMBL252581	0.71	MAPT (0.60)	SMN1; SMN2MAPTHTR1ADRD2HDAC3
	Hydrochloric Acid SCHEMBL28989961	0.71	LOXL2 (0.55)	SMN1; SMN2MAPTHTR1ADRD2HDAC3
	SCHEMBL7014940	0.71	CHRM1 (0.39)	ALDH1A1KDM4ESMN1; SMN2HPGDRAB9A
	SCHEMBL23804835	0.70	CYP1A2 (0.51)	SMN1; SMN2RAB9ANPC1MAPK1DRD2
	SCHEMBL13597091	0.70	HDAC3 (0.69)	ALDH1A1KDM4ENPC1FAAHMEN1
	SCHEMBL8688187	0.70	MAPT (0.63)	SMN1; SMN2MAPTDRD2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.