Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | ACP1 | P24666 | 4/20 | 0.52 |
| ▸ | BAG3 | O95817 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463951 | 1.00 | PIM1 (0.58) | PIM1MEN1POLBKMT2AHSP90AA1 | |
| SCHEMBL15682751 | 0.81 | MEN1 (0.61) | MEN1POLBKMT2AHSP90AA1GAA | |
| SCHEMBL15682752 | 0.81 | MEN1 (0.78) | MEN1POLBKMT2AHSP90AA1GAA | |
| SCHEMBL5465596 | 0.81 | MEN1 (0.74) | MEN1POLBKMT2AHSP90AA1GAA | |
| SCHEMBL5465601 | 0.81 | MEN1 (0.74) | MEN1POLBKMT2AHSP90AA1GAA | |
| SCHEMBL5462486 | 0.80 | CFTR (0.62) | PIM1NLRP3PTPN1ACP1SLC2A1 | |
| SCHEMBL5462482 | 0.80 | CFTR (0.62) | PIM1NLRP3PTPN1ACP1SLC2A1 | |
| SCHEMBL5462396 | 0.80 | NLRP3 (0.62) | PIM1NLRP3PTPN1ACP1SLC2A1 | |
| SCHEMBL5462391 | 0.80 | NLRP3 (0.62) | PIM1NLRP3PTPN1ACP1SLC2A1 | |
| SCHEMBL5463673 | 0.79 | SLC2A1 (0.55) | PIM1MEN1POLBKMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | PIM1 1268/4885MEN1 2892/4885POLB 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.