Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33527682 | 0.93 | TSHR (0.46) | TSHRMETAP1MAPTMEN1KMT2A | |
| SCHEMBL29459210 | 0.87 | ALDH1A1 (0.45) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL40372 | 0.87 | ALDH1A1 (0.45) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6552336 | 0.85 | ALDH1A1 (0.44) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| Lithium SCHEMBL6552341 | 0.85 | ALDH1A1 (0.44) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28338025 | 0.83 | ALDH1A1 (0.42) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21694418 | 0.82 | METAP1 (0.52) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL311978 | 0.82 | ALDH1A1 (0.45) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29471001 | 0.82 | ALDH1A1 (0.45) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL868504 | 0.81 | ALDH1A1 (0.53) | TSHRMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110294-B2 | Fluorene compound; steric hindrance | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20080200736-A1 | MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200736-A1 | MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME | LEF1, FMNL1, AFF1 | TSHR 2376/4885METAP1 1845/4885MAPT 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.