SCHEMBL546476

SCHEMBL546476

Fc1ccc([S+](c2ccccc2)c2ccccc2)cc1.O=C(OCCCCCCCCCCCCCCCI)C(F)(F)S(=O)(=O)[O-]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
PTGS2 P35354 1/20 0.30
BCHE P06276 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547298 1.00 TDP1 (0.33) TDP1HDAC1HDAC2PTGS2BCHE
SCHEMBL547031 1.00 TDP1 (0.33) TDP1HDAC1HDAC2PTGS2BCHE
SCHEMBL546340 0.94 TDP1 (0.36) TDP1HDAC1HDAC2PTGS2
SCHEMBL547113 0.94 TDP1 (0.36) TDP1HDAC1HDAC2PTGS2
SCHEMBL547273 0.90 TDP1 (0.33) TDP1HDAC1HDAC2BCHEHSD11B1
SCHEMBL547285 0.90 TDP1 (0.35) TDP1
SCHEMBL546521 0.89 HDAC1 (0.33) TDP1HDAC1HDAC2BCHE
SCHEMBL547199 0.89 TDP1 (0.35) TDP1HDAC1HDAC2PTGS2BCHE
SCHEMBL546322 0.89 TDP1 (0.35) TDP1HDAC1HDAC2PTGS2BCHE
SCHEMBL547330 0.89 HDAC1 (0.33) TDP1HDAC1HDAC2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524440-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-03 US disclosed
US-8110336-B2 Resin and chemically amplified resist composition comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-07 US disclosed
US-20110165513-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY LTD (JP) 2011-07-07 US disclosed
US-20100075257-A1 Resin and Chemically Amplified Resist Composition Comprising the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-25 US disclosed