Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470386 | 0.85 | TRPV1 (0.59) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL5468865 | 0.85 | MAPT (0.61) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL14363407 | 0.81 | TRPV1 (0.62) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL2700887 | 0.80 | TRPV1 (0.76) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL5060499 | 0.79 | P2RX1 (0.72) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL330023 | 0.79 | TMPRSS4 (0.83) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL5457589 | 0.78 | P2RX1 (0.66) | SMN1; SMN2TMPRSS4MEN1KMT2AMAPT | |
| SCHEMBL330058 | 0.77 | TMPRSS4 (0.67) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL10910605 | 0.77 | TRPV1 (0.67) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 | |
| SCHEMBL330554 | 0.77 | TMPRSS4 (0.67) | TRPV1TSHRSMN1; SMN2TMPRSS4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | TRPV1 3489/4885TSHR 2228/4885SMN1; SMN2 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.