Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470861 | 0.84 | NPSR1 (0.58) | CYP1A2CYP2C9ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5477980 | 0.83 | ALDH1A1 (0.43) | CYP1A2CYP2C9ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5472814 | 0.83 | CYP1A2 (0.43) | CYP1A2CYP2C9ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5477950 | 0.83 | MEN1 (0.56) | CYP1A2CYP2C9ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5476994 | 0.82 | CYP17A1 (0.47) | CYP1A2CYP2C9ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5460274 | 0.82 | ALDH1A1 (0.55) | CYP1A2CYP2C9ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5458575 | 0.80 | GAA (0.52) | ALDH1A1SMN1; SMN2RAB9ANPSR1NPC1 | |
| SCHEMBL5460284 | 0.79 | ALDH1A1 (0.45) | CYP1A2CYP2C9ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5467291 | 0.78 | CCNT1 (0.44) | CYP1A2CYP2C9ALDH1A1KDM4EAAK1 | |
| SCHEMBL5472490 | 0.78 | ALDH1A1 (0.52) | CYP1A2CYP2C9ALDH1A1CYP3A4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | CYP1A2 500/4885CYP2C9 499/4885ALDH1A1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.