SCHEMBL546569

SCHEMBL546569

CO[Si](CCC(C)Oc1ccc(N2CCCCC2=O)cc1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.42
F2 P00734 3/20 0.42
LMNA P02545 1/20 0.42
SLC29A1 Q99808 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
MAPT P10636 1/20 0.42
LIPE Q05469 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TP53 P04637 1/20 0.40
ACACB O00763 1/20 0.40
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547249 0.99 F10 (0.43) F10F2LMNASLC29A1ALDH1A1
SCHEMBL546821 0.96 ALDH1A1 (0.46) F10F2LMNAALDH1A1HPGD
SCHEMBL546621 0.89 USP2 (0.39) F10F2LMNASLC29A1ALDH1A1
SCHEMBL547076 0.88 USP2 (0.39) F10F2LMNASLC29A1ALDH1A1
SCHEMBL546774 0.85 ALDH1A1 (0.42) LMNAALDH1A1HPGDMAPTLIPE
SCHEMBL547454 0.80 HTT (0.48) F10F2LMNASLC29A1ALDH1A1
SCHEMBL546307 0.79 HTT (0.47) F10F2LMNASLC29A1ALDH1A1
SCHEMBL611715 0.77 F10 (0.57) F10F2LMNASLC29A1ALDH1A1
SCHEMBL546226 0.76 HTT (0.52) LMNAALDH1A1HPGDMAPTMEN1
SCHEMBL608919 0.75 F10 (0.58) F10F2SLC29A1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101333272-B Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CO LTD 2012-07-18 CN claimed
US-8110635-B2 Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-07 US claimed
US-20090005497-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US claimed
CN-101333272-B Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CO LTD 2012-07-18 CN disclosed
US-8110635-B2 Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-07 US disclosed
US-20090005497-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed