SCHEMBL547076

SCHEMBL547076

CCO[Si](CCC(C)Oc1ccc(N2CCCCCC2=O)cc1)(OCC)OCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
LIPE Q05469 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
F10 P00742 4/20 0.38
F2 P00734 3/20 0.38
ACACB O00763 1/20 0.38
AKR1C3 P42330 1/20 0.37
LMNA P02545 2/20 0.37
SLC29A1 Q99808 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546621 0.99 USP2 (0.39) USP2LIPEALDH1A1HPGDF10
SCHEMBL546774 0.96 ALDH1A1 (0.42) USP2LIPEALDH1A1HPGDLMNA
SCHEMBL547249 0.89 F10 (0.43) LIPEALDH1A1HPGDF10F2
SCHEMBL546569 0.88 F10 (0.42) LIPEALDH1A1HPGDF10F2
SCHEMBL546821 0.84 ALDH1A1 (0.46) USP2LIPEALDH1A1HPGDF10
SCHEMBL547065 0.81 LMNA (0.46) USP2ALDH1A1F10F2LMNA
SCHEMBL546204 0.80 LMNA (0.47) USP2ALDH1A1F10F2LMNA
SCHEMBL546164 0.76 LMNA (0.50) USP2ALDH1A1HPGDLMNA
SCHEMBL25094272 0.71 LIPE (0.53) USP2LIPEALDH1A1HPGDAKR1C3
SCHEMBL608919 0.70 F10 (0.58) ALDH1A1HPGDF10F2AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110635-B2 Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-07 US claimed
US-20090005497-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US claimed
US-8110635-B2 Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-07 US disclosed
US-20090005497-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed